1. Overview of Succinic acid (CAS NO.: 110-15-6)
Succinic acid, as one white, odorless solid, is a dicarboxylic acid and diprotic acid. For being stable in normal temperature and pressure, this chemical is soluble in water, ethanol and diethyl ether, while insoluble in chloroform and methylene chloride. When comes to its compatibility, it is incompatible with incompatible materials, reducing agents, bases, you should better keep it away from the incompatible materials, in cool, dry and well-ventilated place.
The food-grade Succinic acid has the following detailed technical index: (1)Melting range(oC): 185.0-190.5oC; (2)Chloride %: <=0.007; (3)sulfate(SO42-)%: <=0.02; (4)heavy metal(Counted in Pb2+)%: <=0.001; (5)iron content %: <=0.002; (6)potassium permanganate (Reducing substances): Qualified; (7)Sn Content (As2O3): <=2PPM.
2. Detailed information of Succinic acid (CAS NO.: 110-15-6)
(1). The physico-chemical properties of Succinic acid (CAS NO.: 110-15-6)
With the IUPAC systematic name of butanedioic acid, Succinic acid has its chemical formula of C4H6O4 and molecular weight of 118.09. This chemical could also be called as Amber acid and 1,2-Ethanedicarboxylic acid.
Its other characteristics of Succinic acid are as below: (1)#Freely Rotating Bonds: 3; (2)Polar Surface Area: 74.6; (3)Index of Refraction: 1.478; (4)Molar Refractivity: 23.709 cm3; (5)Molar Volume: 83.814 cm3; (6)Polarizability: 9.399*10-24 cm3; (7)Surface Tension: 61.68 dyne/cm; (8)Density: 1.409 g/cm3; (9)Flash Point: 110.89 oC; (10)Enthalpy of Vaporization: 52.092 kJ/mol; (11)Boiling Point: 236.149 oC at 760 mmHg; (12)Vapour Pressure: 0.01 mmHg at 25oC.
(2). Succinic acid (CAS NO.: 110-15-6) synthesis
A. Chemical method:N,N'-di(2-furoyl)succinic acid dihydrazide could react to produce succinic acid and 2,5-di-furan-2-yl-[1,3,4]oxadiazole. This reaction should happen in the condition of reagent of phosphoryl chloride and solvent of acetonitrile. And it needs 2 hours in heating condition.
B. Common methods:Succinic acid could be prepared from the raw material of Paraffin or Maleic anhydride or fumaric acid.
C. Other method:Crylic acid could react with carbonic oxide in the condition of catalytic agent to achieve the chemical succinic acid. And the chemical equation is as below: CH2 - CHCOOH + CO + H2O - (CH2COOH)2.
(3). Succinic acid (CAS NO.: 110-15-6) applications
Succinic acid could be applied in many different fields, such as be one kind of standard reagent for Alkalimetry, buffer and contrast samples for gas chromatography, and also in the synthesis of dyes and paintings. Besides, it could be used externally for rheumatic aches and pains, and internally in inveterate gleets.
Except the above usage information, this chemical is widely used in the following three big fields.
A. Chemical industry:As the modifier of PH value when in electroplating, strengthening agent for plastics and intermediate of fine chemicals and organic synthesis; In productions of spray paint, dyes, ion exchange resin, pesticide and so on; Applications in dyes, organic pigments, rubber vulcanization accelerator, alkyd resin, adhesive, lubricants, papermaking chemicals, plant growth promoters, photographic chemicals, surface active agent, ion/change resin, pesticide, fungicide and cosmetics.
B. Medicine industry:In the synthesis of sedative, diuretic, vitamin, contraceptive and cancer drugs.
C. Basic organic chemical raw materials:In painting, dyes, adhesive, medicine and so on; In the usage of paper manufacturing and textile industry; As the raw material for lubricant, photographic chemicals and surface active agent.
D. Food industry:In the seasoning of wine, feed, and candy.
(4). Succinic acid (CAS NO.: 110-15-6) safety information
Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-36/37/39-37/39
RIDADR: UN 3265 8/PG 3
WGK Germany: 1
HS Code: 29171990
Hazardous Substances Data: 110-15-6(Hazardous Substances Data)
Succinic acid is irritating to eyes, respiratory system and skin, and it may cause inflammation to the skin or other mucous membranes. Therefore, you should take the following measures to protect yourself from dangers. Firstly, wear suitable protective clothing, gloves and eye/face protection. And if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
(5). Other uses of Succinic acid (CAS NO.: 110-15-6)
Succinic acid could help to produce 3-acridin-9-yl-propionic acid with diphenylamin, with the following reaction. And it needs reagent of ZnCl2 with temperature time of 6 hours and temperature 20 - 200.
(6). Succinic acid Packing (CAS NO.: 110-15-6)
A. Package: 25kg/kraft bag; 500kg/plastic woven bags with inner or requirements according to customers.
(7). Toxicity information of Succinic acid (CAS NO.: 110-15-6)
|| Test Type
|| Reported Dose (Normalized Dose)
|| 2702mg/kg (2702mg/kg)
|| Toxicology. Vol. 62, Pg. 203, 1990.|
|| 1400mg/kg (1400mg/kg)
|| Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 100, 1983.|
|| 2260mg/kg (2260mg/kg)
|| Kodak Company Reports. Vol. #82-0158,|